Dka Diagnosis Uptodate
Abnormalities of dka and hhs in adults will be discussed here.
Dka diagnosis uptodate. Diabetic ketoacidosis dka and hyperosmolar hyperglycemic state hhs also known as hyperosmotic hyperglycemic nonketotic state hhnk are two of the most serious acute complications of diabetes. It occurs at the time of diagnosis of type 1 diabetes in approximately one third of children in the united states 1 5. Dka is characterized by ketoacidosis and hyperglycemia while hhs usually has more severe hyperglycemia but no ketoacidosis. Clinical features and diagnosis of diabetic ketoacidosis in children and adolescents.
1 the biochemical criteria for the diagnosis of dka are hyperglycemia blood glucose level 200 mg dl 11 1 mmol l venous ph less than 7 3 or serum bicarbonate level less than 15 meq l 15 mmol l and ketonemia blood β hydroxybutyrate concentration 3 mmol l or moderate or severe ketonuria. Interestingly patients with euglycemic dka may have a normal mental status despite marked ketoacidosis and vomiting seems to be a common complaint. Euglycemic dka treatment is the same as traditional dka and includes hydration insulin and supportive care. If there isn t enough insulin in your body to allow sugar to enter your cells your blood sugar level will rise hyperglycemia.
They are part of the spectrum of hyperglycemia and each represents an extreme in the spectrum. In children with established diabetes dka occurs at rates of 6 to 8 percent per year 6 7. The clinical features evaluation diagnosis and treatment of these disorders are discussed separately. Less commonly it can occur in children with type 2 diabetes mellitus.
Introduction diabetic ketoacidosis dka is the leading cause of morbidity and mortality in children with type 1 diabetes mellitus. Diabetic ketoacidosis dka is characteristically. Introduction diabetic ketoacidosis dka is the leading cause of morbidity and mortality in children with type 1 diabetes mellitus. Dka is caused by absolute or relative insulin deficiency.
Diabetic ketoacidosis dka and hyperosmolar hyperglycemic state hhs also known as hyperosmotic hyperglycemic nonketotic state hhnk are two of the most serious acute complications of diabetes. Diabetic ketoacidosis dka is characteristically associated with type 1 diabetes. Blood tests used in the diagnosis of diabetic ketoacidosis will measure.